{"search_session":{},"preferences":{"l":"en","queryLanguage":"en"},"patentId":"US_6875751_B2","frontPageModel":{"patentViewModel":{"ref":{"entityRefType":"PATENT","entityRefId":"045-936-573-735-049"},"entityMetadata":{"linkedIds":{"empty":true},"tags":[],"collections":[{"id":11855,"type":"PATENT","title":"University of Montpellier Patent Portfolio","description":"","access":"OPEN_ACCESS","displayAvatar":true,"attested":false,"itemCount":11808,"tags":[],"user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"notes":[{"id":8467,"type":"COLLECTION","user":{"id":91044780,"username":"Cambialens","firstName":"","lastName":"","created":"2015-05-04T00:55:26.000Z","displayName":"Cambialens","preferences":"{\"usage\":\"public\",\"beta\":false}","accountType":"PERSONAL","isOauthOnly":false},"text":"
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
Search Applicants and Owners separately:univ* AND Montpellier. Select more for logical variants. Add to collection. Select all patents in the collection and expand by simple families. Add to collection. Total patents: 1289
or a pharmaceutically acceptable salt thereof, wherein\n
R2 is an amino acid residue; and\n
R3 and R4 are independently H, straight chained, branched or cyclic alkyl, dialkylaminoalkylene, CO-alkyl, CO-aryl, CO-alkoxyalkyl, CO-aryloxyalkyl, CO-substituted aryl, alkylsulfonyl, arylsulfonyl, aralkylsulfonyl, amino acid residue, mono, di, or triphosphate, or a phosphate prodrug."],"number":3,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 3, wherein R2 is an amino acid residue of the formula C(O)C(R8)(R9)(NR10R11), wherein\n
R8 is the side chain of an amino acid and wherein R8 can optionally be attached to R10 to form a ring structure; or alternatively, R8 is an alkyl, aryl, heteroaryl or heterocycle;\n
R9 is hydrogen, alkyl or aryl; and\n
R10 and R11 are independently hydrogen, acyl or alkyl."],"number":4,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 4, wherein R2 is L-valinyl."],"number":5,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 3, wherein R3 and R4 are hydrogen."],"number":6,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 3, wherein R3 is hydrogen and R4 is dimethylaminomethylene."],"number":7,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 3, wherein R3 is hydrogen and R4 is CO-alkyl."],"number":8,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 3, wherein R3 is hydrogen and R4 is CO-methyl."],"number":9,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 3, wherein R3 is hydrogen and R4 is L-valinyl."],"number":10,"annotation":false,"title":false,"claim":true},{"lines":["A compound of the formula: \n\n
or a pharmaceutically acceptable salt thereof, wherein\n
R2is an amino acid residue."],"number":11,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 11, wherein R2 is an amino acid residue of the formula C(O)C(R8)(R9)(NR10R11), wherein\n
R8 the side chain of an amino acid and wherein R8 can optionally be attached to R10 to form a ring structure; or alternatively, R8 an alkyl, aryl, heteroaryl or heterocycle;\n
R9 is hydrogen, alkyl or aryl; and\n
R10 and R11 are independently hydrogen, acyl or alkyl."],"number":12,"annotation":false,"title":false,"claim":true},{"lines":["The compound of claim 12, wherein R2 is L-valinyl."],"number":13,"annotation":false,"title":false,"claim":true},{"lines":["A pharmaceutical composition comprising an effective anti-HBV amount of a compound of the formula: \n\n
or a pharmaceutically acceptable salt thereof, wherein\n
R2 is an amino acid residue; and\n
R3 and R4 are independently H, straight chained, branched or cyclic alkyl, dialkylaminoalkylene (in particular, dimethylaminomethylene), CO-alkyl, CO-aryl, CO-alkoxyalkyl, CO-aryloxyalkyl, CO-substituted aryl, alkylsulfonyl, arylsulfonyl, aralkylsulfonyl, amino acid residue, mono, di, or triphosphate, or a phosphate prodrug; with a pharmaceutically acceptable carrier or diluent."],"number":14,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 14, wherein R2 is an amino acid residue of the formula C(O)C(R8)(R9)(NR10R11), wherein\n
R8 is the side chain of an amino acid and wherein R8 can optionally be attached to R10 to form a ring structure; or alternatively, R8 is an alkyl, aryl, heteroaryl or heterocycle;\n
R9 is hydrogen, alkyl or aryl; and\n
R10 and R11 are independently hydrogen, acyl or alkyl."],"number":15,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 15, wherein R2 is L-valinyl."],"number":16,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 14, wherein R3 and R4 are hydrogen."],"number":17,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 14, wherein R3 is hydrogen and R4 is dimethylaminomethylene."],"number":18,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 14, wherein R3 is hydrogen and R4 CO-alkyl."],"number":19,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 14, wherein R3 is hydrogen and R4 is CO-methyl."],"number":20,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 14, wherein R3 is hydrogen and R4 is L-valinyl."],"number":21,"annotation":false,"title":false,"claim":true},{"lines":["A pharmaceutical composition comprising an effective anti-HBV amount of a compound of the formula: \n\n
or a pharmaceutically acceptable salt thereof, wherein\n
R2 is an amino acid residue;\n
with a pharmaceutically acceptable carrier or diluent."],"number":22,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 22, wherein R2 is an amino acid residue of the formula C(O)C(R8)(R9)(NR10R11), wherein\n
R8 is the side chain of an amino acid and wherein R8 can optionally be attached to R10 to form a ring structure; or alternatively, R8 is an alkyl, aryl, heteroaryl or heterocycle;\n
R9 is hydrogen, alkyl or aryl; and\n
R10 R11 are independently hydrogen, acyl or alkyl."],"number":23,"annotation":false,"title":false,"claim":true},{"lines":["The pharmaceutical composition of claim 23, wherein R2 is L-valinyl."],"number":24,"annotation":false,"title":false,"claim":true},{"lines":["A pharmaceutical composition comprising a compound of the formula \n\n
or a pharmaceutically acceptable salt thereof, with a pharmaceutically acceptable carrier or diluent."],"number":25,"annotation":false,"title":false,"claim":true}]}},"filters":{"npl":[],"notNpl":[],"applicant":[],"notApplicant":[],"inventor":[],"notInventor":[],"owner":[],"notOwner":[],"tags":[],"dates":[],"types":[],"notTypes":[],"j":[],"notJ":[],"fj":[],"notFj":[],"classIpcr":[],"notClassIpcr":[],"classNat":[],"notClassNat":[],"classCpc":[],"notClassCpc":[],"so":[],"notSo":[],"sat":[]},"sequenceFilters":{"s":"SEQIDNO","d":"ASCENDING","p":0,"n":10,"sp":[],"si":[],"len":[],"t":[],"loc":[]}}